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G Protein-Coupled Receptors in Drug Discovery (Drug by Kenneth H. Lundstrom,Mark L. Chiu PDF

By Kenneth H. Lundstrom,Mark L. Chiu

The wide diversity of G protein-coupled receptors (GPCRs) encompasses all components of recent drugs and feature a big effect at the strategy of drug improvement. utilizing disease-oriented ways to disguise every thing from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in a variety of human illnesses.

The ebook offers present techniques in drug discovery that come with goal choice, institution of screening and sensible assays. It additionally covers recombinant GPCR expression for drug screening and structural biology, diversified equipment for structural characterization of GPCRs, and the significance of bioinformatics. The ebook has been rigorously edited to prevent overlapping info, a few duplication has been deliberately accepted in order that every one bankruptcy can functionality as an self sufficient unit. delivering in-depth discussions on constitution and dynamics of GPCRs, this publication outlines the significance of the GPCRs to drug discovery regularly and drug objectives specifically.

Daniel E. Levy, editor of the Drug Discovery Series, is the founding father of DEL BioPharma, a consulting carrier for drug discovery courses. He additionally keeps a web publication that explores natural chemistry.

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G Protein-Coupled Receptors in Drug Discovery (Drug Discovery Series) by Kenneth H. Lundstrom,Mark L. Chiu

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